Flucostat a few days before conception. Is Flucostat possible in early and late pregnancy

Many women are accustomed to treating thrush or vaginal candidiasis with the drug Flucostat based on fluconazole. However, is it possible to drink the antifungal drug Flucostat during pregnancy and, especially on early dates? Before answering this question, it is worthwhile to carefully understand what it is and what effect this medicine has.

When is Flucostat prescribed?

Thanks to the active substance fluconosol, the drug Flucostat is considered a very effective antifungal agent. Along with the treatment of thrush, the drug is effective in many infectious diseases provoked by various fungi:

Generalized candidiasis.
Mucosal candidiasis.
Cryptococcal inflammation of the meninges (infectious meningitis).
Cryptococcal pneumonia.
Mycoses of the skin.
Pityriasis versicolor.

Flucostat may be used to prevent fungal infection in immunocompromised patients.

Side effects

In most cases, Flucostat is well tolerated. As a rule, with prolonged use or intravenous administration of the drug, the following adverse reactions can be observed, which at the same time quickly disappear after the end of treatment:

Nausea.
Vomit.
Dizziness.
Headache.
Slight pain in the abdomen.
Violation of the liver, kidneys.
Allergic reactions.

Application features

To date, full-fledged clinical studies on the effect of an antifungal drug on the development and formation of the fetus have not been conducted. According to the official instructions, Flucostat can be taken during pregnancy, but only in particularly extreme cases, when there is a threat to the life of the expectant mother, for example, with generalized candidiasis.

In the vast majority of cases, treating thrush with Flucostat during pregnancy, especially in the early stages, is not only not worth it, but even impossible. Fortunately, there are many other antifungal drugs that can cope with thrush without compromising the health of the mother and fetus.

It is strongly not recommended to drink Flucostat from vaginal candidiasis during pregnancy and during breastfeeding.

What can replace Flucostat?

Oddly enough, but almost all antifungal agents are dispensed in a pharmacy without a prescription, which leads to their uncontrolled use. No matter how sure you are about the appropriateness of using a particular drug, you must first tell your doctor about it.

If Flucostat is not recommended for drinking during pregnancy, this does not mean that there are no other drugs that can be used to treat common thrush. The following antifungal medications are effective for vaginal candidiasis and are approved for use during pregnancy:

Pimafucin.
Livarol.
Terzhinan.
Polygynax.

The use of fluconazole-containing drugs during pregnancy, such as Flucostat or Diflucan, is possible only in especially extreme cases, life threatening women.

Pimafucin

The antibacterial drug Pimafucin with the active ingredient natamycin has a pronounced antifungal effect. Due to its effectiveness, this antibiotic has been successfully used to treat vaginal candidiasis and other infectious diseases fungal nature, the pathogens of which are sensitive to natamycin.

Nevertheless, it should be noted some adverse reactions that may occur on Pimafucin. When ingested, nausea and diarrhea are sometimes observed at the beginning of treatment, which, as a rule, disappear after a few days. If the antibiotic is applied to the skin and mucous membranes, there may be a burning sensation and some tissue irritation.

Currently, Pimafucin is one of the few antifungal drugs that is completely safe when used during pregnancy and during breastfeeding. The average price for a pack of tablets (20 pieces) is 460 rubles. Vaginal suppositories, as well as 2% cream for external use, will cost about 270 rubles.

Livarol

The drug Livarol contains the active substance ketoconazole and has a fairly high antifungal activity. The drug has a therapeutic and prophylactic effect in fungal infections of the female genital organs.

Adverse reactions are quite rare. However, if they occur, it is usually itching, redness, or slight irritation of the mucous membrane.

Unlike Flucostat, the antifungal drug Livarol can be used during pregnancy, but only in the 2nd and 3rd trimester (after the 12th week). There are no restrictions for use during the feeding period. In most pharmacies, Livarol vaginal suppositories produced pharmaceutical company"Nizhpharm", sold at a price of 400 rubles for 5 pieces.

Terzhinan

The complex antibacterial drug Terzhinan, which contains several active substances (ternidazole, neomycin, nystatin), has a wide range of applications. As a rule, it is used in the following cases:

Bacterial vaginosis.
Infectious and inflammatory processes in the vagina of various nature.
Trichomoniasis.
For preventive purposes during childbirth, abortion and various gynecological operations.

In the early stages of pregnancy, the drug "Terzhinan" is contraindicated. In the 2nd and 3rd trimesters, the attending physician decides on the advisability of prescribing this drug. In addition, Terzhinan should also be used with extreme caution during breastfeeding. The price varies from 360 to 450 rubles, depending on the number of vaginal tablets in the package.

Do not be lazy to read the instructions for the drug, even if it was prescribed to you by an experienced qualified specialist. If you have any doubts or questions about your prescribed medications, do not hesitate to contact your doctor again.

Polygynax

The active ingredients neomycin, nystatin and polymyxin, which are part of the drug Polygynax, have a pronounced antibacterial and antifungal effect, therefore it is often used for vaginal candidiasis and various types inflammation of the vagina and cervix.

Without the approval of a doctor during the period of bearing a child and breastfeeding, Polygynax is strictly forbidden to be used in the treatment of thrush and other infectious pathologies of the genital organs. A package of vaginal capsules, consisting of 6 pieces, is sold in a pharmacy at a price of 320 rubles.

It is possible to treat thrush in the early stages of pregnancy, but not with such antifungal agents as Flucostat, Diflucan and other fluconazole-containing drugs.

The medicine that is right for you should be prescribed exclusively by the attending physician after a detailed examination and clinical diagnosis.

Pregnant women should take any medication with caution. And even if the drugs were ideal for them before the onset of an “interesting situation”, this does not mean that they can be used without fear in a new incarnation. This warning also applies to drugs for carrying a baby. Can Flucostat be used during this period?

Medications and early pregnancy

Early pregnancy is the first trimester, the period before. As a rule, in the first month, a woman rarely knows about her new position. And in fairness, it is worth noting that pregnancy for many women is not always a planned event. Nevertheless, having decided to endure it and give birth to a child, you need to know that it is in the first twelve weeks that the formation of all the organs of the future crumbs, the systems of his body takes place. Taking medications in such a crucial period is always a risk, especially if the drugs are of chemical origin. It is very dangerous to take antibiotics in the first trimester. This category of drugs in itself and for healthy person dangerous, has many side effects. And what can we say about the effect on the body of a pregnant woman! That is why doctors strongly recommend that you contact your gynecologist about the use of any medicines in the early stages of gestation.

Thrush and Flucostat

A common disease is provoked by yeast-like fungi. Nowadays, the pharmaceutical industry offers a wide range of drugs to eliminate thrush. One of them is Flucostat. In such an antifungal drug, the main active ingredient is fluconazole. By the way, it is he who is the basis of other remedies against thrush - analogues of Flucostat. These are Difluzol, Futsis, Diflucan, Flucoside, Mikosist. Such funds have proven themselves in the treatment of candidiasis in ordinary women.

Flucostat in the treatment of thrush in pregnancy

In the early stages of bearing a baby, candidiasis often develops. And this contributes to the decrease in the immunity of women.

However, for the treatment of candidiasis at this stage, it is forbidden to use all drugs based on fluconazole, including Flucostat. They are not allowed during lactation. The reason is that such drugs actively penetrate into the fluids and tissues of the body, they act even through the placental barrier. Flucostat has toxic effect and on fungal infection, and on the body of a child developing in utero.

The drug was assigned category C for the effect on the fetus. This means that its action has been experimentally tested on animals and a negative effect on the fetus has been proven. Of course, for humane reasons, such studies have not been conducted on pregnant women. On the one hand, this may justify their use, but on the other hand, it poses a huge risk for the child.

That is why obstetrician-gynecologists refrain from prescribing Flucostat in early pregnancy and beyond. They replace the medicine with other antifungal drugs that are safer and do not create negative impact to the fruit. Flucostat can only be used for generalized candidal lesions, that is, in the case when it can threaten life future mother. Then the benefit to her is estimated higher than the harm done to the fetus. But in practice, such situations rarely occur.

It is worth knowing that the generalized course of candidiasis is the transition of an ordinary thrush into the vagina into a large-scale chronic infection of the body by a fungus. This is facilitated by serious diseases that violate the body's immune defenses. We are talking about leukemia, diabetes, HIV infection. In such cases, the use of Flucostat by doctors is allowed. In other situations, the use of the drug in the early stages of bearing a child is prohibited. The doctor may recommend that the woman apply prescriptions traditional medicine e.g. douching baking soda or infusion of chamomile.

And in order to avoid unpleasant situations with symptoms of thrush, pregnant women in the early stages should especially carefully observe personal hygiene, wear underwear made from natural fabrics, and avoid sexual contact with casual partners.

Thrush is a common female disease caused by yeast-like fungi. Thrush does not go away on its own, it must be treated. In principle, at present, pharmacies offer a lot of effective drugs from this disease including flucostat. However, is flucostat possible during pregnancy?

Indeed, in this most important period for a woman, the appearance of thrush can pose a real threat to the course of pregnancy and the health of the baby, and taking many drugs during gestation is prohibited. How to be?

Indications for the use of flucostat during pregnancy

Flucostat during pregnancy is contraindicated. In rare cases, when certain conditions are created, a fungal infection can cover the entire body. A severe generalized course of candidiasis with damage to external and internal tissues and organs can be fatal in 75% of cases. At the same time, the lack of necessary therapy, even an ordinary thrush in the vagina or in oral cavity can turn into a large-scale chronic fungal infection. Often this is facilitated by other serious diseases that violate the immune defenses in the body: diabetes, leukemia, HIV infection.

If such a situation is created that it is not so much the state of pregnancy and the preservation of the fetus that comes to the fore, but the life of a pregnant woman, then in this case the use of flucostat is allowed.

In all other cases, the use of the drug during pregnancy is contraindicated.

Is flucostat possible during pregnancy?

Flucostat is an antifungal drug, which is represented by the active substance fluconazole. This substance commonly used to treat candidiasis, both in women and men. Drugs such as fucis, difluzol, diflucan, mycosyst, flucoside are all synonyms for the drug flucostat based on fluconazole.

It remains to be added that without exception, all fluconazole preparations (including flucostat) are prohibited for use during pregnancy, as well as during breastfeeding. The fact is that this drug actively penetrates into all tissues and body fluids, including through the placental barrier. Fluconazole has a toxic effect not only on a fungal infection, but also on some vital processes of the body, including the body of a growing baby in utero.

For the treatment of thrush during pregnancy, there are other, less toxic drugs. Flucostat is permissible to use only with generalized candidal lesions, when a fungal infection can threaten the life of a pregnant woman. In such cases, the benefit to the woman is valued higher than the harm done to the child.

Flucostat when planning pregnancy

If you are using flucostat when planning a pregnancy, then the appropriateness of using the drug should be evaluated by your doctor. It is recommended to first treat thrush or candidiasis, and only after that proceed with planning a pregnancy. If a fungal infection caught you at the planning stage, then the best solution would be to postpone conception, or use other antifungal drugs that are not prohibited during pregnancy.

The fact is that the pharmacological properties of flucostat are somewhat specific: the active component fluconazole is distributed to all tissues in the body. Its excretion through the kidneys is slow, over several weeks. Remains of the substance are found in the nail tissue even six months (!) After the end of flucostat treatment. Given the accumulation of the drug in the body and its slow excretion, it is recommended to treat with flucostat before planning pregnancy.

Flucostat in early pregnancy

Pilot studies conducted at a Danish research institute determined the effect of the active component of flucostat in early pregnancy. Scientists have found that the use of a medication in the first weeks of pregnancy can provoke the development of heart defects in the unborn baby.

Unfortunately, there are often cases when a woman takes a flucostat in the early stages, not yet knowing about her “position”. But just in the first weeks of gestation, at the beginning of the first trimester, at the time when the formation of the heart system and organs of the fetus occurs, many medications are very, very dangerous.

Scientists analyzed the health indicators of children who were born between 1996 and 2011. During the experiment, it was found that in those women who took flucostat in the first weeks of pregnancy or later, the statistics of the incidence of their children with congenital heart disease was three times higher .

Previous studies have already proven that the use of large doses of flucostat in the first weeks of pregnancy can cause a number of birth defects in newborns, such as defects in the musculoskeletal system, defects in the mouth and face, etc.

Contraindications to the use of flucostat during pregnancy

A contraindication to the use of flucostat during pregnancy is, in fact, the pregnancy itself.

Flucostat is classified as an FDA fetal category C.

What does this mean?

The U.S. Department of Health's Office of Drug Control has identified a number of potential hazards to the fetus from drug use by pregnant women. This list has six categories: flucostat in this list is classified in category C. This category includes those drugs that have been experimentally tested on animals, and their negative impact on the fetus has been proven. However, the same studies in humans with these drugs have not been conducted, which, on the one hand, may justify their use, but, on the other hand, this poses a considerable risk for a developing child.

For this reason, experts are trying to refrain from prescribing flucostat, replacing this drug with other antifungal agents that definitely do not have a damaging effect on the fetus.

Side effects of flucostat during pregnancy

For a long time, there were no reports of any side effects of flucostat on the fetus and pregnancy. However, there is now information that newborns whose mothers during three months or more used uncontrolled amounts of the drug fluconazole, found various birth defects. Of course, direct studies on this subject have not been conducted, but on this moment it is generally accepted that the use of fluconazole (the active ingredient of flucostat) at a dosage of 400 mg / day can adversely affect the development of the fetus.

Vaginal candidiasis is one of the most common gynecological problems in women, since this place is a favorable breeding ground for yeast, and it is easy to bring them there. During pregnancy, immunity drops dramatically, the load on the body increases significantly, as a result of which it becomes more susceptible to harmful bacteria, viruses and fungi. Drugs for thrush are becoming the most popular means to eliminate the symptoms of candidiasis, but can they be taken by pregnant women, during what period are they safest and can they be drunk at the planning stage?

Description of the medicinal product

Flucostat is the strongest fungicidal agent with a wide range exposure, which in a matter of days destroys fungal activity and reduces the manifestation of unpleasant symptoms. Flucostat is one of the analogues of fluconazole, this is its active substance. Despite the speed and effectiveness of the drug, the following negative side effects may develop as a result of taking it:

Severe diarrhea and loss of appetite
Bloating and flatulence
Vomiting and nausea
Malfunctions in the liver, a strong hepatotoxic effect
Headache, loss of consciousness and dizziness
Seizures
Cardiopalmus
Bleeding from the vagina
Alopecia and severe hair loss
Allergy.

Looking at such a list of side effects, it becomes clear that taking flucostat during pregnancy, especially in the early stages, is highly discouraged. However, there are severe fungal infections in a pregnant woman and if they are not treated, they will penetrate the child's body and cause irreparable harm. In this case, it is necessary to immediately treat the disease, and the attending physician selects the specific drug. It happens that it is necessary to prescribe a flucostat.

It is best taken with caution in the 3rd trimester as internal organs the fetus and system are already fully formed. From the above, we can conclude that the medication is prescribed only if the intended benefit outweighs the potential harm to the fetus and mother.

when planning a pregnancy

The period before conception is a very important stage, since the mother's body is prepared as much as possible before the upcoming pregnancy. All necessary tests are given, and if during laboratory research thrush is detected, then it must be treated carefully and before complete disappearance. If a flucostat is taken, then conception is delayed for several months, since this drug spreads well throughout all tissues of the body, and is excreted along with urine after a long period of time. If a woman accidentally became pregnant and did not know about it, but drank this medication in the early stages, it is recommended to inform the attending physician immediately. The specialist must take this situation seriously, taking all necessary monitoring measures.

What is the risk of taking the drug in the first trimester

Based on the research data obtained, the active substance of the drug, taken in the first trimester, can negatively affect the fetal body, causing abnormalities in the development of the heart muscle. It has been established that this remedy has congenital malformations and pathologies of the fetus, therefore it is not prescribed either during pregnancy or during lactation.

How can you treat thrush during gestation

According to statistics, thrush in pregnant women occurs at least once during the entire period in 80% of cases. It is impossible to tolerate a painful condition, otherwise it will only worsen, which from a local vaginal lesion can go into a chronic or systemic form. There is a limited list of drugs that can be used.

From 13-14 weeks you can use vaginal tablets, pimafucin suppositories, livarol and clotrimazole cream. In the earliest stages, the use of pimafucin is possible. Tableted forms of release during the period of bearing a child are prohibited, as they have a systemic effect on the entire body. It is possible to receive complex treatment of thrush only after the birth of a child.

If a woman is overtaken by thrush during the period of gestation, then you should immediately contact your doctor so that he can select the necessary gentle drug. It is forbidden to engage in self-selection of medicines, because the correct dosages are needed, which can only be established by a specialist. Self-medication is dangerous to health, the same applies to traditional medicine, which can be very harmful, even if they helped painlessly before.

Thrush (candidiasis) in pregnant women is more common than in other women. Such activity of the disease is due to the fact that during the period of bearing a child, cardinal changes occur in the woman's body, weakening immune system. As a result, pathogens begin to manifest themselves more actively.

Today, modern pharmacy offers a wide range of medications that successfully cure vaginal candidiasis in women. One of such effective means can be called Flucostat. Due to the fact that many drugs cannot be taken by pregnant women, there is natural question Is it possible during pregnancy Flucostat?

Composition and form of release of the drug

Flucostat (fluconazole) - a powerful antifungal agent of systemic action, adversely affects a number of fungi:

coccidioids.
Cryptococcus.
Candida.

Its main component penetrates into all biological environments of the human body. It inhibits the synthesis of ergosterols (active biological substances), which are necessary for the formation of a cell wall. As a result, under the influence of the drug, pathogens die.

The medicine is prescribed for the treatment of such pathologies:

Cryptococcal meningitis.
Generalized candidiasis.
Candidiasis of the oral mucosa.
Genital candidiasis.
endemic mycoses.
For the prevention of fungal infections.

The composition of the drug

Your high healing effect the drug shows, thanks to the special substances in its composition. The preparation contains:

Fluconazole (active substance).
Lactose.
Corn starch.
Aerosil (colloidal silicon dioxide).
Magnesium stearate.
Sodium lauryl sulfate.

Release form of the drug

Today, Flucostat can be purchased in pharmacies in several pharmacological forms:

Vaginal suppositories.
Solution for intravenous injection.
Capsules.
Tablets.

Which option is acceptable for your case, the attending physician will tell you. However, a pregnant woman, before purchasing the drug, must definitely consult her gynecologist, since many drugs are contraindicated during the period of bearing a child. The specialist will tell you whether it is possible to take Flucostat from thrush during pregnancy, because during pregnancy it can be used very rarely, therefore, he will prescribe a more gentle medication more often.

What are the features of taking the drug during pregnancy?

Vaginal candidiasis, which is manifested by itching, burning and extraneous discharge, causes significant discomfort to a pregnant woman. Trying to get rid of the disease, the woman goes through everything possible options drugs that are acceptable for treatment in her position.

Is it allowed to be treated with Flucostat during pregnancy?

Flucostat is a rather aggressive drug that penetrates deeply into the human body. In addition, there have been no thorough studies on this drug, and scientists do not know all the subtleties of its effect on the body of the mother and fetus. There is evidence that taking flucostat during early pregnancy provoked the development of various anomalies in the unborn child. In particular, Danish scientists have found that the use of Flucostat during early pregnancy caused the development of abnormal heart defects in the fetus. Due to its teratogenic properties, the drug can cause the development of deformity.

On the Internet you can find a lot of information where women admit that they took this medicine during their pregnancy, and everything went fine. After reading such reviews, some expectant mothers are lost and do not know how to do the right thing: listen to the doctor's recommendations (who does not advise taking this remedy), or still take the risk, since Flucostat cured her neighbor Manya or girlfriend Varya from thrush, And the baby is fine too!

The official instructions for the use of Flucostat during pregnancy (https://medi.ru/instrukciya/flyukostat_939/) clearly states:

The drug is prescribed to pregnant women only in cases where it is necessary to save the life of the mother!

In other words, the medicine is prescribed only for health reasons. In other cases, the drug is not prescribed for women in position!

I would like to add that all medicines in which the active ingredient fluconazole is strictly prohibited for pregnant / lactating women, because of its ability to penetrate deep into the placenta. In addition, fluconazole has a pronounced toxic nature, which affects not only the fungal infection, but also the intrauterine development of the baby.

It is also worth emphasizing that the pharmacological characteristics of the drug are a little specific:

Its active component fluconazole is able to spread throughout the body.
Fluconazole is excreted very slowly by the kidneys (over several weeks).
Its residues are found in the nail tissues even 6 months after the last medication.

In what doses is the drug prescribed during pregnancy?

As already mentioned above, taking a drug such as Flucostat is not recommended for pregnant women. However, there are situations when it is expedient to appoint him.

During pregnancy, the capsules are prescribed in the following dose: 400 mg of the drug 1 time / day for 14 days or more, if necessary according to indications.

The therapeutic effect of the capsule is noted already 3 hours after its administration. The intensity of burning and itching is noticeably reduced. On the second day of treatment, the obvious symptoms of thrush practically disappear.

With regard to Flucostat suppositories during pregnancy, their dosage is prescribed in individually, based on the degree of development of the disease and the condition of the pregnant woman herself.

The duration of treatment averages 7-14 days.

You can use vaginal suppositories of the drug at any time of the day, when it is convenient for the patient.

Contraindications and side effects

In addition to the fact that the drug is prescribed for pregnant women in exceptional cases, in fact, the drug has many more contraindications that pregnant women should be aware of. First of all, that it is necessary to refuse to take Flucostat when planning a pregnancy. In the event that they were treated with this antifungal medicine and planned to conceive a child, it is necessary to wait for some time until the remnants of the medication are completely removed from the body.

Often a woman is interested in what will happen if she drinks Flucostat during pregnancy? If the medication was taken in a single case, there should not be any special problems for the child, however, be sure to notify the doctor about this fact so that he can more closely monitor the child and be able to detect deviations in the intrauterine development of the fetus in a timely manner.

Other contraindications to the use of Flucostat during pregnancy:

Alcoholism.
Renal failure.
Pathology of the liver.
Cardiac arrhythmia.

Side effects

The drug has a high medicinal effect, effectively affects pathogens, but its administration can give a number of side effects:

GIT. Loss of appetite, vomiting, nausea, flatulence, diarrhea, abdominal pain.
CNS. Headache, convulsions, dizziness.
Circulatory system. Decreased leukocyte and platelet counts.
Heart. Violation of the heart rhythm.
Allergy. Urticaria, anaphylactic shock, angioedema, skin rash.
exchange processes. An increase in blood cholesterol, a decrease in the amount of potassium ions in the blood.
Violation of the kidneys.
Baldness.

An overdose of this medication can cause the following serious effects:

paranoid behavior.
hallucinations.

There are no special antidote measures for drug overdose. Symptomatic therapy is used, consisting in gastric lavage and the appointment of sorbents. In some cases, forced diuresis and hemodialysis are recommended.

How does the drug interact with other drugs?

The annotation to the drug states that a single / multiple use of Flucostat in a low dose (50 mg) together with Antipyrine does not cause side effects.

However, you should not combine the medication with the following medications:

Cisapride.
Terfenadine.
Astemizol.
Pimozide.
Quinidine.
Erythromycin.

In addition, be careful and carefully determine the dosage while treating Flucostat and such drugs:

Hydrochlorothiazide.
Rifampicin.
Alfentanil.
Amitriptyline.
Nortriptyline.
Amphotericin B.
Azithromycin and a number of other medicines.

In any case, whether or not to combine Flucostat with other drugs is decided by the attending physician.

What are the analogues of the drug?

To date, pharmacies offer a sufficient range of drugs, the effect of which is similar to the medicinal abilities of Flucostat. What can replace Flucostat during pregnancy? Before giving an answer, the expectant mother should not forget that any, even harmless medicine, must be taken only with the consent of the attending gynecologist.

Below is a list of analogues of the drug, however, all of them contain the same active substance as in Flucostat, therefore, be careful when buying these drugs:

Flucanosole.
Flucanosole Sandoz.
Diflucan.
Medoflucon.
Tsiskan.
Mycosist.
Nofung.
Fluconorm.
Flucosan and others.

As you can see, Flucostat is absolutely not harmless. medicine which is completely prohibited for pregnant women. It is used only in the treatment of generalized candidiasis, when the disease threatens the life of a pregnant woman. If there is no urgent need for its use, the doctor will definitely advise a more gentle version of the medicine, which is allowed for the treatment of thrush during the period of bearing the baby.